Are you an adult who has serious health problems because of your weight Have you tried diet and exercise but haven't been able to lose enough weight If you answered yes to these questions, a prescription weight-loss drug may be a choice for you.
Before choosing a medicine for you, your health care provider thinks about your history and health challenges. Then your provider talks with you about the pros and cons of prescription weight-loss drugs.
Prescription weight-loss drugs that you can use for more than 12 weeks, called long-term use, lead to major weight loss compared with an inactive treatment that doesn't use medicine, called a placebo. The combination of weight-loss medicine and lifestyle changes leads to greater weight loss than do lifestyle changes alone.
Taking these drugs for a year can mean a loss of total body weight of 3% to 12% more than that lost with lifestyle changes alone. That may not seem like a lot. But losing 5% to 10% of your total weight and keeping it off can have important health benefits. For example, it can lower blood pressure, blood sugar levels and levels of fats in the blood called triglycerides.
How long you take a weight-loss drug depends on whether the drug helps you lose weight. If you've lost enough weight to improve your health and you haven't had serious side effects, your health care provider may suggest that you take the drug long term.
If you haven't lost at least 5% of your body weight after taking the full dose of a drug for 3 to 6 months, your health care provider will probably change your treatment. They may switch you to a different weight-loss drug.
Phentermine-topiramate is a combination of a weight-loss drug called phentermine and an anticonvulsant called topiramate. Phentermine has the potential to be misused because it acts like a stimulant drug called an amphetamine. Other possible side effects include an increase in heart rate and blood pressure, insomnia, constipation, and nervousness. Topiramate increases the risk of birth defects.
Phentermine by itself (Adipex-P, Lomaira) also is used for weight loss. It's one of four similar weight-loss drugs approved for use for less than 12 weeks, called short-term use. The other drugs in this group aren't often prescribed.
To take the drug, you'll need to have test results that show you have one of these conditions. Setmelanotide doesn't treat any of the gene problems that cause these conditions. But it can help you lose weight. It can lessen your appetite and make you feel fuller. And it may help you burn calories while your body is at rest.
Excess weight requires lifelong management. Weight issues are progressive as we age, and frequently excess weight returns. Obesity is a chronic condition that places your health at risk, however, there are various options for managing and treating excess weight. Prescription weight loss drugs are now considered a frontline treatment. Your weight is classified as obese if your body mass index (BMI) is 30 or higher.
The medication semaglutide (Wegovy) received FDA approval for treatment of obesity in 2021. More common prescription weight loss drugs which have been in use longer include liraglutide (Saxenda), naltrexone-bupropion (Contrave), orlistat (Alli, Xenical), and phentermine-topiramate (Qsymia ).
Before you get a weight loss drug prescription, tell your doctor about your medical history. That includes any allergies or other conditions you have; medicines or supplements you take (even if they're herbal or natural); and whether you're pregnant, breastfeeding, or planning to get pregnant soon.
What else you should know: If you don't lose 4% of your weight after 16 weeks of taking Liraglutide, your doctor may tell you to stop taking it, because it's unlikely to work for you, the FDA says.
How it works: Mounjaro is a first-in-class medicine that activates both the hormones GLP-1 and GIP receptors and leads to improved blood sugar control. During tirzepatide diabetes trials, researchers noted people who got tirzepatide lost much more weight than those on standard diabetes therapy.
What else you should know: If you don't lose 5% of your weight after 12 weeks of taking Contrave, your doctor may tell you to stop taking it, because it's unlikely to work for you, the FDA says. Taken together they appear to signal the brain to decrease food intake.
Qsymia combines phentermine with the seizure/migraine drug topiramate. Topiramate causes weight loss in several ways, including helping you feel full, making foods taste less appealing, and burning more calories.
Serious side effects include certain birth defects (cleft lip and cleft palate), faster heart rate, suicidal thoughts or actions, and eye problems that could lead to permanent vision loss if not treated.
What else you should know: If you don't lose at least 3% of your weight after 12 weeks on Qsymia, the FDA recommends that you stop taking it or that your doctor increase your dose for the next 12 weeks -- and if that doesn't work, you should gradually stop taking it.
Serious eye problems, which include any sudden decrease in vision, with or without eye pain and redness or a blockage of fluid in the eye causing increased pressure in the eye (secondary angle closure glaucoma). These problems can lead to permanent vision loss if not treated. Tell your healthcare provider right away if you have any new eye symptoms.
Numbness or tingling in the hands, arms, feet, or face (paraesthesia); dizziness; changes in the way foods taste or loss of taste (dysgeusia); trouble sleeping (insomnia); constipation; and dry mouth.
Increases of acid in bloodstream (metabolic acidosis). If left untreated, metabolic acidosis can cause brittle or soft bones (osteoporosis, osteomalacia, osteopenia), kidney stones, can slow the rate of growth in children, and may possibly harm your baby if you are pregnant. Metabolic acidosis can happen with or without symptoms. Sometimes people with metabolic acidosis will: feel tired, not feel hungry (loss of appetite), feel changes in heartbeat, or have trouble thinking clearly. Your healthcare provider should do a blood test to measure the level of acid in your blood before and during your treatment with Qsymia.
Low blood sugar (hypoglycemia) in people with type 2 diabetes mellitus who also take medicines used to treat type 2 diabetes mellitus. Weight loss can cause low blood sugar in people with type 2 diabetes mellitus who also take medicines used to treat type 2 diabetes mellitus (such as insulin or sulfonylureas). You should check your blood sugar before you start taking Qsymia and while you take Qsymia.
For adult patients with a body mass index (BMI) of 30+ or 27 kg/m2 or greater (overweight) in the presence of at least one weight-related medical condition or pediatric patients aged 12 years and older with an initial BMI in the 95th percentile or greater standardized for age and sex.
The FDA has found tainted weight loss products. In recent years, the FDA has discovered hundreds of dietary supplements that contain potentially harmful drugs or other chemicals not listed on the product label. Many of these products are for weight loss and bodybuilding.
These pills aren't a perfect solution for obesity. Weight loss medications are used along with a healthy diet and exercise regimen that need to be continued after treatment. Also, side effects are common and can be severe.
In fact, many manufacturers of weight loss supplements don't test their products in humans before taking them to market. What's more, the FDA has warned that some over-the-counter products contain hidden ingredients. These include prescription drugs and controlled substances like sibutramine, which was removed from the market in 2010 because it substantially increased heart rate and blood pressure.
One such ingredient is Garcinia cambogia, which comes in products like Hydroxycut and Plexus Slim. It's supposed to suppress appetite and decrease the number of fat cells your body makes. Though it's considered \"fairly safe,\" there's no evidence that it actually helps with weight loss, and excessive use has been linked to liver problems.
Other diet pills may contain chitosan, from the shells of crabs, lobsters, and shrimp. In theory, it's supposed to bind fat in your digestive tract so your body can't absorb it. In reality, according to the NIH, the amount of fat it binds is probably not enough to help you lose a significant amount of weight.
The most common ingredients are stimulants like caffeine, yerba mate, bitter orange, or guarana. When it comes to the data on these ingredients, there's not a lot to suggest they help in any way with weight loss, said Katherine Zeratsky, a registered dietitian at the Mayo Clinic.
Theoretically, all these ingredients should help with weight loss, but it's extremely difficult to figure out if they work, Zeratsky said. That's because most diet pills are made up of multiple ingredients and the directions suggest you take them while having a diet that's restrictive in calories. So it's hard to tell whether you lost weight because of the product or because you simply ate fewer calories.
Through this work, we have been made aware of a number of illegal weight-loss products which all contain the active substance sibutramine appearing neither from the product declaration nor the package. The products, which are often sold on the internet, can be dangerous to health, and we therefore warn consumers against using them. Sibutramine has previously been authorised for the treatment of obesity, but it also causes a number of serious side effects, and all authorised sibutramine-containing medicines were taken off the market in 2010.
We do not know of all illegal weight-loss products on the market, and it is likely that other illegal and hazardous weight-loss products are in circulation; any such products do not appear on the below list of illegal weight-loss products.
People who have a BMI between 25 and 30 are considered to be overweight. Obesity is defined as having a BMI of 30 or greater. You can calculate your BMI to learn if you are overweight, have obesity, or have severe obesity, which may increase your risk of health problems. Your health care professional can assess your individual risk caused by your weight. 59ce067264